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1 Strip of Levitra (Vardenafil as Hydrochloride Trihydrate) 10mg Tablet

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5.00 LBS
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Product Description

Product Description

Product Name:

Levitra 20mg,

film-coated tablets

vardenafil (as hydrochloride trihydrate)

4 film-coated tablets


Generic Name:


Vardenafil

Indication:

LEVITRA is a prescription medicine used for the treatment of erectile dysfunction (ED) in men.

Important Safety Information:

LEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke.

Do not take LEVITRA if you:

Take any medications called "nitrates" (often used to control chest pain, also known as angina), or if you use recreational drugs called "poppers" like amyl nitrate and butyl nitrate. Nitrates may cause abnormally low blood pressure and LEVITRA may increase that risk.

Have been told by your healthcare provider not to have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.
    Tell all your healthcare providers that you take LEVITRA. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took LEVITRA.

LEVITRA does not protect a man or his partner from sexually transmitted diseases, including HIV.

Before taking LEVITRA, tell your doctor about all your medical problems, including if you:

        have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack—ask your doctor if it is safe for you to have sexual activity
        have low blood pressure or have high blood pressure that is not controlled
        have had a stroke
        have had a seizure
        or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome)
        have liver problems
        have kidney problems and require dialysis
        have retinitis pigmentosa, a rare genetic (runs in families) eye disease
        have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION)
        have stomach ulcers
        have a bleeding problem
        have a deformed penis shape or Peyronie's disease
        have had an erection that lasted more than 4 hours
        have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia
        have hearing problems

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. LEVITRA and other medicines may affect each other. Especially tell your doctor if you take any of the following:

Ritonavir (Norvir®) or indinavir sulfate (Crixivan®), saquinavir (Fortavase® or Invirase®) or atazanavir (Reyataz®), or other HIV protease inhibitors

Ketoconazole or itraconazole (such as Nizoral® or Sporanox®)
        
Erythromycin or clarithromycin:

Tell your doctor if you take alpha-blockers. These include Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), or Rapaflo® (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients the use of PDE5 inhibitor drugs, including LEVITRA, with alpha-blockers can lower blood pressure significantly, leading to fainting.

Contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider.

Tell your doctor if you take medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone, and sotalol. Patients taking these drugs should not use LEVITRA.

Do not use LEVITRA with other medicines or treatments for ED.

Take LEVITRA exactly as your doctor prescribes. LEVITRA comes in different doses (2.5 mg, 5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Do not take more than one tablet of LEVITRA per day. Doses should be taken at least 24 hours apart. Some men can take only a low dose of LEVITRA because of medical conditions or medicines they take.
Your doctor will prescribe the dose that is right for you:

        If you are older than 65 or have liver problems, your doctor may start you on a lower dose of LEVITRA
        If you have prostate problems or high blood pressure for which you take medicines called alpha-blockers, your doctor may start you on a lower dose of LEVITRA
        If you are taking certain other medicines your doctor may prescribe a lower starting dose and limit you to one dose of LEVITRA in a 72-hour (3 days) period.

The most common side effects with LEVITRA are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness, and back pain.

LEVITRA may uncommonly cause:

An erection that lasts more than 4 hours. Get medical help right away to avoid lasting damage to your penis.

Color vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green.

In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including LEVITRA) reported a sudden decrease or loss of vision in one or both eyes or a sudden decrease or loss in hearing, sometimes with ringing in the ears and dizziness. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience sudden decrease or loss of vision or hearing, stop taking LEVITRA and contact a doctor right away.

Please read the Patient Information and discuss it with your doctor.

The physician Prescribing Information is also available.

DRUG CLASS AND MECHANISM:

Vardenafil is an oral drug that is used to treat impotence, the inability to attain or maintain a penile erection. It has a mechanism of action that is similar to sildenafil (Viagra), and tadalafil (Cialis). Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase in size and increase the delivery of blood to the penis. At the same time, the blood vessels carrying blood away from the penis decrease in size and decrease the removal of blood from the penis. Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively. Vardenafil prevents an enzyme called phosphodiesterase-5 (PDE-5) from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis. Vardenafil was approved by the FDA in August 2003.

PRESCRIPTION:

Yes

GENERIC AVAILABLE:

No

PREPARATIONS:

Tablets: 2.5, 5, 10 and 20 mg. Tablet (orally disintegrating): 10 mg.

STORAGE:

Vardenafil should be stored at room temperature between 15-30 C (59-86 F).

PRESCRIBED FOR:

Vardenafil is used for the treatment of impotence.

DOSING:

For most individuals, the recommended dose of vardenafil regular tablets is 10 mg per day taken 60 minutes before intercourse. If there is no response or side effects, the dose may be increased to 20 mg or, if there are side effects, it may be reduced to 5 mg.

Individuals 65 years of age or older should begin therapy with 5 mg.

Individuals who are taking medications that increase the blood levels of vardenafil should start treatment with 2.5 to 5 mg of vardenafil. (See drug interactions.)

Orally disintegrating tablets (ODT) are not interchangeable with regular vardenafil tablets because they are better absorbed and produce higher blood levels than regular tablets. The recommended dosing when using ODT is one tablet 60 minutes before intercourse. Only one tablet should be used per day. It should be placed on the tongue until it disintegrates and should not be swallowed with water.

DRUG INTERACTIONS:

The breakdown and elimination of vardenafil from the body is inhibited by erythromycin, clarithromycin (Biaxin), ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan), ritonavir (Norvir), atazanavir (Reyataz), grapefruit juice. Therefore, these drugs increase the concentration of vardenafil in the blood and should not be combined with vardenafil. Vardenafil reduces the concentration of ritonavir and indinavir and may reduce the effect these drugs. Vardenafil increases heart rate and also exaggerates blood pressure lowering effects of nitrates (for example, nitroglycerine). In patients with chest pain (angina), particularly those who take nitrates,, vardenafil can cause chest pain by increasing heart rate and lowering blood pressure. Therefore, patients with angina should not use vardenafil. Vardenafil also exaggerates the blood pressure lowering effects of alpha-blocking drugs, for example, terazosin (Hytrin), and should not be used by individuals who also use alpha-blockers. Vardenafil also adds to the blood pressure reducing effect of other medications.

PREGNANCY:

Vardenafil is not approved for use in women.

NURSING MOTHERS:

Vardenafil has not been evaluated in women who are breastfeeding.

SIDE EFFECTS:

The most common side effects of vardenafil are facial flushing (reddening), headaches, stomach upset, diarrhea, flu like symptoms, and nausea. Vardenafil also may cause chest pain, low blood pressure, blurred vision and changes in color vision, abnormal ejaculation and priapism (painful erection lasting more than 6 hours). Patients should seek immediate medical help if they experience an erection lasting more than 4 hours. Rare cases of sudden loss of hearing have been reported with phosphodiesterase inhibitors such as vardenafil, sometimes associated with ringing in the ears and dizziness. If changes in hearing occur, patients should discontinue their vardenafil and seek immediate medical attention.


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